Description
The Human Mitochondrial Genome: From Basic Biology to Disease, (PDF) is an essential resource that offers an extensive and current analysis of human mitochondrial genomics, bridging the gap between foundational research and its application in translational medicine across various disease spectrums. This detailed ebook features contributions from international experts who delve into the intricate biology of human mitochondrial DNA (mtDNA), covering critical aspects such as its maintenance, repair mechanisms, inheritance patterns, and segregation processes.
The text also explores mtDNA evolution, its functional exploitation, and the implications of mutations, while offering methodologies and models relevant for conducting functional studies of mtDNA. In addition to the foundational biology, the book provides an in-depth examination of numerous diseases linked to mtDNA, including but not limited to cancer, age-related disorders, mtDNA depletion syndromes, neurodegenerative diseases, as well as diseases driven by deletions and point mutations. Therapeutic strategies are thoroughly discussed, with innovative treatments like nucleoside supplementation, mitoZNF, and mitoTALENs nucleases featured prominently.
As interest in mitochondrial DNA continues to gain momentum, supported by increased funding for mtDNA research, clinicians and researchers are increasingly focusing on the associations between mitochondrial genome variations and various diseases. This ebook equips readers with the necessary tools and foundational knowledge to embark on cutting-edge research in this dynamic field, empowering them to identify haplogroup-defining variants or disease-specific mutations, and to discover emerging therapeutic avenues.
- Provides comprehensive insights into vital research protocols and innovative perspectives tailored for aspiring scientists.
- Features contributions from a diverse and authoritative international team, spanning from basic biologists to clinician-scientists, ensuring a well-rounded discussion.
- Presents in-depth disease discussions complemented by practical diagnostic and therapeutic strategies that are currently being adopted in clinical settings.
- Thoroughly investigates recent advancements and technological breakthroughs in the field, paving the way for novel mtDNA studies, variant identification, pathogenic assessment, and therapy development.
IMPORTANT: This product consists solely of the ebook, The Human Mitochondrial Genome: From Basic Biology to Disease, available in PDF format. Please note that no access codes are included.
ISBN-13: 978-1627031316
ISBN-10: 1627031318
Reviews
There are no reviews yet.